"person or persons in constant suffering of body or mind," 1650s, noun use of past participle adjective from afflict.
late 14c., "to cast down," from Old French aflicter, from Latin afflictare "to damage, harass, torment," frequentative of affligere (past participle afflictus) "to dash down, overthrow," from ad- "to" (see ad-) + fligere (past participle flictus) "to strike," from PIE root *bhlig- "to strike" (cf. Greek phlibein "to press, crush," Czech blizna "scar," Welsh blif "catapult"). Transferred meaning of "trouble, distress," is first recorded 1530s. Related: Afflicted; afflicting.