side effect

noun
1.
any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.
2.
any accompanying or consequential and usually detrimental effect:
the side effects of air pollution.
Also, side-effect.
Origin
1880-85
British Dictionary definitions for side-effects

side effect

noun
1.
any unwanted nontherapeutic effect caused by a drug Compare aftereffect (sense 2)
2.
any secondary effect, esp an undesirable one
Word Origin and History for side-effects

side effect

n.

also side-effect, 1884, from side (adj.) + effect (n.). Medical use, with reference to drugs, is recorded from 1939.

side-effects in Medicine

side effect n.
A peripheral or secondary effect, especially an undesirable secondary effect of a drug or therapeutic regimen.