1743, borrowed during an outbreak of the disease in Europe, from Italian influenza "influenza, epidemic," originally "visitation, influence (of the stars)," from Medieval Latin influentia (see influence). Used in Italian for diseases since at least 1504 (cf. influenza di febbre scarlattina "scarlet fever") on notion of astral or occult influence. The 1743 outbreak began in Italy. Often applied since mid-19c. to severe colds.
influenza in·flu·en·za (ĭn'flōō-ěn'zə)
n.
An acute contagious viral infection, commonly occurring in epidemics or pandemics, and characterized by inflammation of the respiratory tract and by the sudden onset, fever, chills, muscular pain, headache, and severe prostration. Also called grippe.
Commonly called the flu; an acute and infectious disease of the respiratory system caused by a virus and characterized by fever, muscle pain, headache, and inflammation of the mucous membranes in the respiratory tract.