1830, from hypo- "under" + derma "skin" + -ic.
hypodermic hy·po·der·mic (hī'pə-dûr'mĭk)adj.
Of or relating to the layer just beneath the epidermis.
Relating to the hypodermis.
Injected beneath the skin.
A hypodermic injection.
A hypodermic needle.
A hypodermic syringe.