1. Contagious, infectious are usually distinguished in technical medical use. Contagious, literally “communicable by contact,” describes a very easily transmitted disease as influenza or the common cold. Infectious refers to a disease involving a microorganism that can be transmitted from one person to another only by a specific kind of contact; venereal diseases are usually infectious. In nontechnical senses, contagious emphasizes the rapidity with which something spreads: Contagious laughter ran through the hall. Infectious suggests the pleasantly irresistible quality of something: Her infectious good humor made her a popular guest.