1876, in writings on Greek drama, from Greek agonistes, literally "combatant in the games" (see agony).
agonist ag·o·nist (āg'ə-nĭst)
n.
A contracting muscle that is resisted or counteracted by an antagonistic muscle.
A substance that can combine with a cell receptor to produce a reaction typical for that substance.
agonist (āg'ə-nĭst)
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