C16: from Greek Argonautēs, from Argō the name of Jason's ship + nautēs sailor
Word Origin and History for Argonaut
n.
"sailor of the Argo," 1580s (implied in argonautic), from Argo + Greek nautes "sailor" (see naval). Adventurers in the California Gold Rush of 1848 were called argonauts (because they sought the golden fleece) by those who stayed home.