a suffix found in French loanwords of Latin origin, usually diminutives, and later in adaptations of words borrowed directly from Latin or in Neo-Latin coinages:
areole; centriole; vacuole.
Origin
< French < Latin-olus, -ola, -olum, variant of -ulus-ule with stems ending in a vowel
-ole2
1.
a suffix used in names of chemical compounds, especially five-membered, unsaturated rings (carbazole; indole; thiazole) and, less systematically, aromatic ethers (anisole; safrole).