-o-

1.
the typical ending of the first element of compounds of Greek origin (as -i-, is, in compounds of Latin origin), used regularly in forming new compounds with elements of Greek origin and often used in English as a connective irrespective of etymology:
Franco-Italian; geography; seriocomic; speedometer.
Compare -i-.
Origin
Middle English (< Old French) < Latin < Greek
British Dictionary definitions for -o-

-o-

connective vowel
1.
used to connect elements in a compound word: chromosome, filmography Compare -i-
Word Origin
from Greek, stem vowel of many nouns and adjectives in combination
-o- in Medicine

-o-
Used as a connective to join word elements: acidophilic.